Location History:
- Chapel Hill, NC (US) (2020)
- Iowa City, IA (US) (2019 - 2021)
Company Filing History:
Years Active: 2019-2021
Title: Thad Sharp: Innovator in Epithelial Cell Generation and Bone Regeneration
Introduction
Thad Sharp is a prominent inventor based in Iowa City, IA (US), known for his significant contributions to the fields of cellular biology and regenerative medicine. With a total of 4 patents, Sharp has focused on innovative methods to generate epithelial cells and enhance bone regeneration.
Latest Patents
One of Sharp's latest patents involves methods to generate epithelial cells. This invention provides a method of generating a re-programmed differentiated epithelial cell by contacting a non-stem somatic cell with a de-differentiation agent to form a de-differentiated cell. The process continues with transfecting the de-differentiated cell with an expression cassette that includes a promoter linked to a nucleic acid encoding a conversion agent. Additionally, the invention outlines methods for using these re-programmed differentiated epithelial cells to repair or regenerate tissue in vivo. Another notable patent focuses on microRNA-200 based approaches for modulating bone formation inhibition and bone regeneration. This invention utilizes microRNA (miR)-200a to inhibit ossification and promote bone formation.
Career Highlights
Thad Sharp is affiliated with the University of Iowa Research Foundation, where he continues to advance his research and innovations. His work has garnered attention for its potential applications in medical therapies and regenerative medicine.
Collaborations
Sharp has collaborated with notable colleagues, including Brad A Amendt and Liu Hong, contributing to the advancement of research in his field.
Conclusion
Thad Sharp's innovative work in generating epithelial cells and enhancing bone regeneration showcases his commitment to advancing medical science. His contributions are paving the way for future breakthroughs in regenerative medicine.