The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 30, 2019
Filed:
May. 01, 2017
Applicant:
University of Iowa Research Foundation, Iowa City, IA (US);
Inventors:
Liu Hong, Iowa City, IA (US);
Brad Amendt, Iowa City, IA (US);
Thad Sharp, Iowa City, IA (US);
Aliasger Salem, Iowa City, IA (US);
Assignee:
University of Iowa Research Foundation, Iowa City, IA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/113 (2010.01); A61L 27/24 (2006.01); A61L 27/56 (2006.01); A61L 27/54 (2006.01); A61K 31/713 (2006.01); A61K 9/16 (2006.01); C12N 7/00 (2006.01); A61K 9/00 (2006.01); A61K 9/51 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 9/0019 (2013.01); A61K 9/1641 (2013.01); A61K 9/1647 (2013.01); A61K 9/5153 (2013.01); A61K 31/713 (2013.01); A61L 27/24 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); C12N 7/00 (2013.01); A61K 48/00 (2013.01); A61L 2300/258 (2013.01); A61L 2300/412 (2013.01); A61L 2430/02 (2013.01); C12N 2310/141 (2013.01); C12N 2320/31 (2013.01); C12N 2320/32 (2013.01); C12N 2330/51 (2013.01); C12N 2740/15043 (2013.01);
Abstract
In certain embodiments, the present invention provides the use of microRNA (miR)-200a and/or miR-200c to inhibit ossification and bone formation. In certain embodiments, the present invention provides the use of miR-200a inhibitor to stimulate bone regeneration.