Tetsuo Kase

Title: Tetsuo Kase: Innovator in Protein Production

Introduction

Tetsuo Kase is a notable inventor based in Osaka, Japan. He has made significant contributions to the field of biotechnology, particularly in the production of proteins with a triple-helix structure. His work focuses on methods that enhance the isolation and purification of human collagen molecules.

Latest Patents

Tetsuo Kase holds a patent for "Methods of producing proteins having triple-helix structure." The objective of this invention is to provide methods for producing human collagen molecules that are easy to isolate and purify. These collagen molecules have a structure that is substantially equivalent to that of natural collagen. The invention involves host cells that are transduced with a collagen gene, which synthesize large amounts of human collagen protein derived from a gene introduced into a high exogenous gene expression vector. The inventors discovered that a significant amount of human collagen, with minimal contamination from host cell-derived collagen, can be produced by selecting a host cell with low collagen expression and introducing a collagen gene construct into a suitable vector.

Career Highlights

Throughout his career, Tetsuo Kase has worked with various organizations, including Fuso Pharmaceutical Industries, Ltd. and the Osaka Prefectural Government. His experience in these institutions has contributed to his expertise in protein production and biotechnology.

Collaborations

Tetsuo Kase has collaborated with notable individuals in his field, including Akio Kimura and Hiroshi Kisaki. These collaborations have likely enhanced his research and development efforts in producing innovative solutions in protein synthesis.

Conclusion

Tetsuo Kase's contributions to the field of biotechnology, particularly in the production of human collagen, highlight his innovative spirit and dedication to advancing scientific knowledge. His work continues to impact the industry positively.