Location History:
- Tokyo, JP (2019)
- Shizuoka, JP (2011 - 2021)
Company Filing History:
7 out of 947 
2 out of 10 
1 out of 1,033 
Years Active: 2011-2021
Title: Tetsuhiro Soeda: Innovator in Blood Coagulation Research
Introduction
Tetsuhiro Soeda is a prominent inventor based in Shizuoka, Japan. He has made significant contributions to the field of blood coagulation, holding a total of 7 patents. His work focuses on improving the accuracy of blood coagulation assessments, particularly for patients with hemophilia A.
Latest Patents
One of Soeda's latest patents is a method for measuring the reactivity of FVIII. In this innovation, he and his team produced substances that neutralize the activity of a bispecific antibody that functionally substitutes for FVIII. They developed methods to measure FVIII reactivity accurately, even in the presence of this bispecific antibody. Their findings revealed that FVIII activity in the plasma of hemophilia A patients can be evaluated accurately using an APTT-based one-stage clotting assay. Additionally, they discovered that FVIII inhibitor titer in the plasma of hemophilia A patients carrying an FVIII inhibitor can also be evaluated accurately using an APTT-based Bethesda assay.
Another significant patent is a method for evaluating blood coagulation reactions. Soeda's research involved studying various methods for evaluating hemostatic effects and blood coagulation initiation reagents. He constructed a method for evaluating blood coagulation reactions mediated by substances that substitute for coagulation factor VIII (FVIII). The results indicated that using a coagulation initiation reagent containing activated coagulation factor XI (FXIa) and phospholipids allows for the evaluation of the effect of FVIII substitutes on blood coagulation reactions, using the amount of thrombin generated in the blood sample as an indicator.
Career Highlights
Throughout his career, Tetsuhiro Soeda has worked with notable organizations, including Chugai Pharmaceutical Co., Ltd. and Nara Medical University. His experience in these institutions has contributed to his expertise in blood coagulation research and innovation.
Collaborations
Soeda has collaborated with several professionals in his field, including Takehisa Kitazawa and Tomoyuki Igawa. These collaborations have further enhanced his research and development efforts in blood coagulation.
Conclusion
Tetsuhiro Soeda's innovative work in blood coagulation research has led to significant advancements in the evaluation of FVIII activity and blood coagulation reactions. His contributions are
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