The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 22, 2019
Filed:
Apr. 19, 2016
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Tomoyuki Igawa, Shizuoka, JP;
Zenjiro Sampei, Shizuoka, JP;
Tetsuo Kojima, Shizuoka, JP;
Tetsuhiro Soeda, Shizuoka, JP;
Atsushi Muto, Shizuoka, JP;
Takehisa Kitazawa, Shizuoka, JP;
Yukiko Nishida, Shizuoka, JP;
Chifumi Imai, Shizuoka, JP;
Tsukasa Suzuki, Shizuoka, JP;
Kazutaka Yoshihashi, Shizuoka, JP;
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Abstract
Various bispecific antibodies that specifically bind to both blood coagulation factor IX/activated blood coagulation factor IX and blood coagulation factor X and functionally substitute for the cofactor function of blood coagulation factor VIII, that is, the function to promote activation of blood coagulation factor X by activated blood coagulation factor IX, were produced. From these antibodies, multispecific antigen-binding molecules having a high activity of functionally substituting for blood coagulation factor VIII were successfully discovered.