Chiba, Japan

Tetsuaki Arai



Average Co-Inventor Count = 5.0

ph-index = 1

Forward Citations = 3(Granted Patents)


Location History:

  • Nagareyama, JP (2014)
  • Chiba, JP (2015)
  • Tokyo, JP (2015)

Company Filing History:


Years Active: 2014-2015

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3 patents (USPTO):Explore Patents

Title: Tetsuaki Arai: Innovator in Neurodegenerative Disease Research

Introduction

Tetsuaki Arai is a prominent inventor based in Chiba, Japan. He has made significant contributions to the field of neurodegenerative diseases through his innovative research and patented inventions. With a total of 3 patents, Arai's work focuses on understanding and diagnosing conditions such as frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).

Latest Patents

Arai's latest patents include groundbreaking inventions that address critical aspects of neurodegenerative diseases. One of his notable patents is the TDP-43-storing cell model. This invention discloses a transformed cell capable of forming a cytoplasmic inclusion body derived from TAR DNA-binding protein of 43 kDa (TDP-43). This protein is commonly found in the brains of patients suffering from neurodegenerative diseases. The transformed cell is characterized by the introduction of a promoter that functions effectively in a host cell, along with a mutant TDP-43 gene.

Another significant patent involves an antibody that specifically binds to an abnormal TDP-43 protein aggregate. This invention provides an agent comprising the antibody for detecting TDP-43 proteinopathy lesions. Additionally, it outlines a method for detecting or diagnosing TDP-43 proteinopathy lesions using the antibody.

Career Highlights

Tetsuaki Arai is affiliated with the Tokyo Metropolitan Institute of Medical Science, where he conducts his research. His work has been instrumental in advancing the understanding of neurodegenerative diseases and developing potential diagnostic tools.

Collaborations

Arai collaborates with esteemed colleagues in his field, including Takashi Nonaka and Haruhiko Akiyama. Their combined expertise contributes to the ongoing research and innovation in neurodegenerative disease studies.

Conclusion

Tetsuaki Arai's contributions to the field of neurodegenerative diseases through his patents and research are invaluable. His innovative approaches to understanding and diagnosing these conditions highlight the importance of continued research in this critical area of medicine.

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