Terry L Bray

Title: The Innovative Contributions of Terry L. Bray

Introduction

Terry L. Bray is a prominent inventor based in Birmingham, Alabama, recognized for her significant contributions to the field of protein crystallization. With four patents to her name, she has demonstrated a remarkable ability to innovate and develop methods that enhance the understanding of protein structures.

Latest Patents

One of Bray's latest patents is titled "Method for screening crystallization conditions in solution crystal growth." This patent describes a novel approach for screening protein crystal growth conditions, utilizing picogram to microgram amounts of protein in tiny volumes. The method incorporates a microarray with multiple microchambers, where an automated dispensing mechanism introduces protein solutions into the micro-chambers. By adjusting the crystallization conditions in each chamber differently, she facilitates the crystallization process. The technique allows for observation of protein crystal growth, potentially aided by either a precipitate solution or an oil barrier.

Another notable patent is focused on "Use of dye to distinguish salt and protein crystals under microcrystallization conditions." This innovative method involves crystallizing molecules from solutions containing selectively associated dyes, which aid in color-coding specific crystals for easier detection. This advancement permits the use of smaller solution volumes while enabling extensive screening of crystallization conditions in arrays using automated devices.

Career Highlights

Throughout her career, Bray has worked with esteemed institutions, including the University of Alabama and the UAB Research Foundation. Her work in these organizations has further propelled her research and innovations in crystallization techniques.

Collaborations

Bray has collaborated with notable coworkers, including Lawrence James DeLucas and Larry J. Kim. These collaborations have enriched her research efforts, leading to advancements in her field.

Conclusion

Terry L. Bray is a formidable inventor whose work in protein crystallization methodologies showcases her innovative spirit and dedication to scientific advancement. With her patents and collaborations, she continues to play a vital role in the evolving landscape of biochemistry and molecular biology. Her efforts undoubtedly contribute to a deeper understanding of protein structures and their implications in various scientific fields.