Company Filing History:
Years Active: 1998-2006
Title: Terence Derek Prospero: Innovator in Binding Proteins
Introduction
Terence Derek Prospero is a notable inventor based in Cambridge, GB. He has made significant contributions to the field of biochemistry, particularly in the development of multivalent and multispecific binding proteins. With a total of 3 patents, his work has implications for various applications in medical research and therapeutic development.
Latest Patents
Prospero's latest patents focus on polypeptides that comprise a first domain, which includes a binding region of an immunoglobulin heavy chain variable region, and a second domain, which includes a binding region of an immunoglobulin light chain variable region. These domains are linked but incapable of associating with each other to form an antigen binding site. They associate to form antigen binding multimers, such as dimers, which may be multivalent or have multispecificity. The domains can be linked by a short peptide linker or may be joined directly together, with bispecific dimers potentially having longer linkers. His patents also disclose methods of preparation for these polypeptides and multimers, as well as their display on the surface of bacteriophage for easy selection of binders of interest.
Career Highlights
Throughout his career, Prospero has worked with esteemed organizations such as the Medical Research Council and Cambridge Antibody Technology Limited. His experience in these institutions has allowed him to refine his expertise in the field of binding proteins and their applications.
Collaborations
Some of his notable coworkers include Andrew David Griffiths and Magnus Malmqvist. Their collaborative efforts have contributed to advancements in the research and development of binding proteins.
Conclusion
Terence Derek Prospero's innovative work in the field of binding proteins has led to significant advancements in biochemistry. His patents and collaborations reflect his commitment to enhancing medical research and therapeutic applications.