Teppei Maruyama

Title: Teppei Maruyama: Pharmaceutical and Medical Packaging Innovations.

Introduction

Teppei Maruyama is an inventor based in Komae, Japan, whose patent work includes pharmaceutical formulations and methods for protecting infusion solutions. His listed portfolio includes 2 patents, and he is associated with Terumo Kabushiki Kaisha, commonly known as Terumo Corporation.

Latest Patents

Maruyama’s patent, “Pharmaceutical composition containing urokinase,” describes an oral formulation designed to improve the intestinal absorption of urokinase, an enzyme that is otherwise vulnerable to breakdown in the stomach and is poorly absorbed through the intestinal tract. The composition combines urokinase with higher fatty acids, a polyalkylene glycol, and calcium. The patent also describes incorporating urokinase into liposomes to support stability and sustained absorption, and using an enteric coating to protect the formulation during passage through the stomach. The composition is proposed for use as a thrombolytic agent.

His patent, “Method for manufacturing plastic container containing infusion solution,” addresses the preservation of infusion solutions containing components that can deteriorate when exposed to oxygen. The method uses a heat-resistant plastic container, packages it in a gas-permeable material, and autoclaves it in a substantially oxygen-free saturated-steam atmosphere. The container is then cooled while maintaining pressure with an inert gas and enclosed in a second package with high oxygen impermeability. This process is intended to help preserve the solution over an extended period.

Career Highlights

Maruyama’s listed inventions address two distinct challenges in medical technology: improving the oral delivery of a therapeutic enzyme and limiting oxygen-related deterioration in infusion solutions. Both patents focus on practical formulation or manufacturing methods intended to support the stability and usability of medical products.

Collaborations

Maruyama is associated with Terumo Corporation. His listed coworkers include Haruo Honda and Noriko Saito.

Conclusion

Teppei Maruyama’s patent work reflects an emphasis on pharmaceutical delivery and medical product preservation, with inventions aimed at improving urokinase absorption and protecting infusion solutions from oxygen exposure.