Potomac, MD, United States of America

Teodor D Brumeanu

USPTO Granted Patents = 2 

 

Average Co-Inventor Count = 3.0

ph-index = 1


Company Filing History:


Years Active: 2017

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2 patents (USPTO):Explore Patents

Title: Teodor D Brumeanu: Innovator in Vaccine Development

Introduction

Teodor D Brumeanu is a notable inventor based in Potomac, MD (US). He has made significant contributions to the field of immunology, particularly in vaccine development. With a total of 2 patents, his work focuses on innovative approaches to enhance the efficacy of vaccines.

Latest Patents

Brumeanu's latest patents include the TH1/TH2 polarizing vaccines. This invention relates to recombinant chimeric molecules that facilitate T cell receptor interaction and costimulation for the activation and differentiation of pathogen-specific T cells into effector T helper 1 (Th1) or T helper 2 (Th2) cells. The chimeras are designed to elicit antibodies against pathogen-specific B cell epitopes. Additionally, the invention encompasses methods for utilizing these chimeric molecules in whole or as components of a vaccine.

Another significant patent is the humanized transgenic mouse model. This model serves as a transgenic animal for testing the immunogenicity and protective efficacy of human vaccines. It includes methods for generating a multitransgenic animal capable of expressing human leukocyte antigen DR4 and human costimulatory molecules (CD80) upon infusion of human HLA-matched hematopoietic stem cells. This model can develop a functional human immune system, providing a valuable tool for vaccine research.

Career Highlights

Teodor D Brumeanu works at the USA as represented by the Secretary of the Navy. His role involves advancing research in immunology and vaccine development, contributing to the broader field of medical science.

Collaborations

Brumeanu collaborates with esteemed colleagues, including Sofia A Casares and Thomas L Richie. Their combined expertise enhances the research efforts in vaccine innovation and development.

Conclusion

Teodor D Brumeanu's contributions to vaccine development through his innovative patents highlight his role as a key figure in immunology. His work continues to pave the way for advancements in human health and disease prevention.

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