Tatsuo Hoshino

This inventor holds 67 USPTO granted patents and 6 published patent applications, plus 3 CIPO patents and 5 EPO patents, primarily in Biochemical Production (CPC class 4351). Top assignees: Roche Vitamins Inc., Hoffmann-La Roche Inc., Dsm IP Assets B.v.. Active years: 1980-2022.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Tatsuo Hoshino. Retrieved from https://idiyas.com/inventor/tatsuo-hoshino

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

USPTO Granted Patents = 67 (Patent Applications = 6)

% Patents Active = 80.6

CIPO Patents = 3 (Patent Applications = 2)

EPO Patents = 5 (Patent Applications = 4)

Average Co-Inventor Count = 3.0

ph-index = 10

Forward Citations = 346(Granted Patents)

Forward Citations (Not Self Cited) = 307(Dec 10, 2025)

Inventors with similar research interests:

Location History:

Fujisawa, JP (1980 - 1981)
Kanagawa-ken, JP (1999 - 2008)
Kamakura, JP (1982 - 2016)
Kawasaki, JP (2021)
Kanagawa, JP (1995 - 2022)

Company Filing History:

Hoffmann-La Roche Inc.

Dsm Nutritional Products Inc.

6. 2 out of 834,570

Other

patents

Years Active: 1980-2022

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Areas of Expertise:

Vitamin C Production

Carotenoid Synthesis

AMPK Activator

Microbial Processes

Isoprenoid Production

Cytochrome c Oxidase

Aldehyde Dehydrogenase

Astaxanthin Production

Biotin Biosynthesis

Gluconobacter

Enzymatic Processes

Genetic Engineering

67 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 11298358 - Combination therapy using ascochlorin derivative (2022-04-12),

2. 10968186 - Ascochlorin derivative and use thereof as AMPK activator (2021-04-06),

3. 9279138 - Vitamin C production in a microorganism, gluconobacter (2016-03-08),

4. 7842483 - Cytochrome c oxidase enzyme complex (2010-11-30),

5. 7687246 - Process for producing carotenoids (2010-03-30),

6. 7670814 - Microbial production of vitamin C (2010-03-02),

7. 7598066 - [object Object] (2009-10-06),

8. 7544494 - Vitamin C from sorbosone (2009-06-09),

9. 7465563 - Enzymatic process for the manufacture of L-ascorbic acid and D-erythorbic acid (2008-12-16),

10. 7432089 - [object Object] (2008-10-07),

11. 7432076 - Astaxanthin production using fed-batch fermentation process by Phaffia rhodozyma (2008-10-07),

12. 7371547 - Process for producing vitamin B6 (2008-05-13),

13. 7351564 - SQS gene (2008-04-01),

14. 7341854 - Microbial production of vitamin C (2008-03-11),

15. 7288395 - ACC gene (2007-10-30),

Title: Innovations and Contributions of Tatsuo Hoshino in Cancer Treatment

Introduction

Tatsuo Hoshino, a prominent inventor based in Kamakura, Japan, has significantly contributed to the medical field with an impressive portfolio of 67 patents. His innovative work primarily focuses on therapies that address diseases involving adenosine monophosphate-activated protein kinase (AMPK) dysregulation, with a particular emphasis on cancer treatment.

Latest Patents

Hoshino's recent patents include groundbreaking advancements such as "Combination therapy using ascochlorin derivative" and "Ascochlorin derivative and use thereof as AMPK activator." The first patent aims to provide a therapeutic solution for diseases involving AMPK dysregulation, particularly cancers, via a combination of a unique compound and an immune checkpoint inhibitor. The second patent introduces a novel ascochlorin derivative designed to activate AMPK, offering potential benefits for the treatment and prevention of relevant diseases.

Career Highlights

Throughout his career, Hoshino has been associated with esteemed companies such as Roche Vitamins Inc. and Hoffmann-La Roche Inc. His work in these organizations has facilitated advancements in biomedical research and therapeutic innovations, positioning him as a key player in his field.

Collaborations

Hoshino has collaborated with fellow researchers and innovators, including Masako Shinjoh and Teruhide Sugisawa. These partnerships have strengthened the research landscape and fostered an environment of creativity and technical advancement.

Conclusion

Tatsuo Hoshino's contributions to the field of cancer therapy highlight the importance of innovation in medicine. His patents not only enhance our understanding of AMPK dysregulation but also pave the way for effective treatments aimed at combating cancer. As he continues to push the boundaries of medical research, his work remains a vital asset to the scientific community.

Profile summary based on public USPTO records.