Company Filing History:
Years Active: 2007
Title: Takumi Mano: Innovator in β-Lactam Acylase Technology
Introduction
Takumi Mano is a notable inventor based in Tatsuno, Japan. He has made significant contributions to the field of biotechnology, particularly in the development of enzymes that enhance antibiotic production. His work has implications for the pharmaceutical industry, especially in the efficient synthesis of important medications.
Latest Patents
Takumi Mano holds 1 patent related to the acylase gene. This invention focuses on a β-lactam acylase protein that exhibits high activity. The patent details a gene coding for this protein, a recombinant vector containing the gene, and a method for producing β-lactam antibiotics such as amoxicillin. The acylase gene was cloned, and its DNA base sequence and amino acid sequence were determined. The resulting protein has a molecular weight of approximately 70 kDa and demonstrates β-lactam acylase activity, allowing for the efficient production of amoxicillin without inhibition from substances like phenylacetic acid. Furthermore, modifications to the amino acid sequence can yield a protein that enhances the production efficiency of amoxicillin.
Career Highlights
Takumi Mano is currently employed at Kaneka Corporation, where he continues to innovate in the field of biotechnology. His research and development efforts have positioned him as a key player in the advancement of antibiotic production technologies.
Collaborations
He collaborates with notable colleagues, including Akiko Nishi and Shinichi Yokota, who contribute to his research endeavors and help drive innovation within their projects.
Conclusion
Takumi Mano's work in the field of β-lactam acylase technology exemplifies the impact of innovative research on pharmaceutical production. His contributions are vital for the development of more efficient methods to produce essential antibiotics.