Company Filing History:
Years Active: 2006-2009
Title: Taka-aki Okamura: Innovator in Protein Modification
Introduction
Taka-aki Okamura is a prominent inventor based in Osaka, Japan. He has made significant contributions to the field of protein and peptide modification, holding a total of 3 patents. His innovative methods have advanced the understanding and application of protein chemistry.
Latest Patents
One of Okamura's latest patents is titled "Methods for derivatizing protein or peptide with sulfonic acid groups." This invention provides a method for effectively introducing sulfonic acid groups into the N-terminus of a protein or peptide. The method involves a modification step that reacts the N-terminus with a compound containing a disulfide group, followed by a cleavage step to convert the disulfide bond into a sulfonic acid group. Additionally, this patent offers a method for analyzing proteins or peptides using mass spectrometry, along with an intermediate for effective derivatization.
Another notable patent is the "Method for modifying protein or peptide C-terminal." This invention presents a simple and cost-effective approach to selectively modify the C-terminal of a protein or peptide. The method includes forming an intramolecular oxazolone ring at the C-terminal, followed by a ring-opening process to produce a modified protein or peptide. This innovative technique allows for the introduction of various nucleophilic groups at the C-terminal, enhancing the versatility of protein modifications.
Career Highlights
Taka-aki Okamura is associated with Shimadzu Corporation, where he continues to develop groundbreaking methods in protein chemistry. His work has garnered attention for its practical applications in various scientific fields, including biochemistry and pharmaceuticals.
Collaborations
Okamura has collaborated with notable colleagues such as Shigemi Norioka and Norikazu Ueyama. Their combined expertise has contributed to the advancement of innovative techniques in protein modification.
Conclusion
Taka-aki Okamura's contributions to the field of protein and peptide modification are noteworthy. His patents reflect a commitment to advancing scientific knowledge and practical applications in biochemistry. His work continues to inspire future innovations in the field.