Tahereh Karimi

Title: Innovations by Tahereh Karimi

Introduction

Tahereh Karimi is an accomplished inventor based in Houston, TX (US). She has made significant contributions to the field of biomedical engineering, particularly in the development of innovative methods for treating cardiovascular diseases and diabetes. With a total of 3 patents, her work has the potential to transform medical practices and improve patient outcomes.

Latest Patents

One of her latest patents is focused on the creation of induced pacemaker and Purkinje cells from adult stem cells. This groundbreaking method involves reprogramming adult stem cells to form pacemaker cells and Purkinje cells through the sequential activation of SHOX2, TBX5, and HCN2. The resulting Purkinje cells spontaneously surround and connect with larger pacemaker cells, forming an induced sinoatrial body that produces funny current, enabling cardiovascular tissues to beat similarly to a natural sinoatrial node.

Another significant patent involves the reprogramming of beta cells from adult stem cells. This patent provides methods for differentiating unmodified adult stem cells into functional beta-like cells. The process requires the sequential expression of PDX1, NGN3, and MAFA in these stem cells to create reprogrammed beta cells. Additionally, methods for treating diabetes are outlined, which include obtaining stem cells from a diabetic patient, inducing the expression of specific genes, and introducing the reprogrammed beta cells into the patient's pancreas.

Career Highlights

Throughout her career, Tahereh Karimi has worked with notable companies such as Ingeneron Incorporated and the Alliance of Cardiovascular Research. Her expertise in stem cell research and regenerative medicine has positioned her as a leader in her field.

Collaborations

One of her prominent collaborators is Eckhard U Alt, with whom she has worked on various innovative projects. Their combined efforts have contributed to advancements in medical technology and treatment methodologies.

Conclusion

Tahereh Karimi's innovative work in the field of biomedical engineering showcases her dedication to improving healthcare through scientific advancements. Her patents reflect her commitment to addressing critical health issues, particularly in cardiovascular and diabetes treatment.