Company Filing History:
Years Active: 2007
Title: The Innovations of Tadashi Nakakarumai
Introduction
Tadashi Nakakarumai is a notable inventor based in Tochigi, Japan. He has made significant contributions to the field of biotechnology, particularly in the development of novel proteins with potential pharmaceutical applications. His work focuses on addressing obesity through innovative protein solutions.
Latest Patents
Tadashi Nakakarumai holds a patent for a novel protein and the processes for producing it. The patent describes a glycoprotein that suppresses the differentiation and maturation of adipocytes. This protein has a molecular weight of approximately 45 kD under non-reducing conditions and about 28 kD and/or 23 kD under reducing conditions. It exhibits affinity to heparin, making it a valuable candidate for pharmaceutical compositions aimed at preventing or treating obesity. The process for producing this protein involves culturing human fibroblasts and purifying the culture broth through chromatography techniques, including ion exchange, affinity, and reverse phase columns. Additionally, a cDNA encoding the protein and a method for producing the protein using the cDNA are also included in the patent.
Career Highlights
Tadashi Nakakarumai is associated with Daiichi Pharmaceutical Co., Ltd., where he continues to innovate in the field of pharmaceuticals. His work has the potential to impact the treatment of obesity and related health issues significantly.
Collaborations
Tadashi has collaborated with notable colleagues, including Masaaki Goto and Akihiro Tomoyasu, to advance his research and development efforts.
Conclusion
Tadashi Nakakarumai's contributions to the field of biotechnology, particularly through his patented protein innovations, highlight his role as a key inventor in addressing obesity. His work exemplifies the intersection of science and health, paving the way for future advancements in pharmaceutical applications.