Durham, NC, United States of America

Sze-Chung Lo


Average Co-Inventor Count = 14.0

ph-index = 2

Forward Citations = 19(Granted Patents)


Company Filing History:


Years Active: 2003-2005

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7 patents (USPTO):Explore Patents

Title: Sze-Chung Lo: Pioneering Inventions in Antifungal Antibiotics

Introduction

Sze-Chung Lo is an accomplished inventor based in Durham, NC, recognized for her significant contributions to the field of antifungal antibiotics. With a total of 7 patents to her name, she has made notable strides in understanding the mechanisms underlying fungal pathogenicity and developing novel methods for combating these infections.

Latest Patents

Among her latest patents, Sze-Chung Lo has introduced innovative methods for the identification of inhibitors of asparagine synthase as antibiotics. Her research has revealed that asparagine synthase plays a crucial role in fungal pathogenicity, and its inhibition can lead to prevention of successful infections and lesions. This invention emphasizes the potential of asparagine synthase as a target for discovering effective antifungal compounds.

In addition, she has developed methods for identifying inhibitors of threonine synthase, another essential enzyme for fungal pathogenicity. The findings indicate that inhibition of threonine synthase gene expression can significantly hinder fungal infection. These methods aim to streamline the process of discovering new antibiotics, particularly antifungals, that could address pressing health concerns related to fungal diseases.

Career Highlights

Sze-Chung Lo has a distinguished career, having worked at notable companies such as Paradigm Genetics, Inc. and Icoria, Inc. Her interdisciplinary approach combines knowledge from genetics, biochemistry, and microbiology, contributing to her innovative research in antibiotic discovery.

Collaborations

Throughout her career, Sze-Chung has collaborated with esteemed colleagues, including Jeffrey R. Shuster and Matthew M. Tanzer. These partnerships have enabled her to explore new avenues in her research and foster a collaborative environment focused on innovation.

Conclusion

Sze-Chung Lo's groundbreaking work in the realm of antifungal antibiotics highlights her expertise and dedication to enhancing public health. With her inventive methodologies aimed at identifying vital enzymatic targets, she continues to contribute significantly to the scientific community and the ongoing fight against fungal pathogens.

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