Company Filing History:
Years Active: 2020-2024
Title: Sylvain Gariel: Innovator in Nucleic Acid Synthesis
Introduction
Sylvain Gariel is a prominent inventor based in Paris, France, known for his contributions to the field of nucleic acid synthesis. With a total of six patents to his name, Gariel's work pushes the boundaries of biotechnology and molecular biology, offering innovative solutions for synthesizing nucleic acids and oligonucleotides.
Latest Patents
Gariel's most recent inventions focus on advanced methods for extending polynucleotides. One of his notable patents is directed towards synthesizing oligonucleotides directly on biomolecules or cells, both living and fixed. This invention employs template-free enzymatic synthesis under biological conditions, using successive cycles of enzymatic addition and deblocking to regenerate a free 3′ hydroxyl. This method has significant implications in the construction and analysis of single-cell cDNA libraries.
Another groundbreaking patent elaborates on a method for synthesizing long nucleic acids. This innovative approach involves multiple elongation cycles of nucleic acid fragments, which include enzymatic addition, purification of correctly sequenced fragments, and optional amplification steps. The method ensures that the fragments are produced in a reaction medium compatible with both enzymatic addition and amplification. Furthermore, Gariel's invention supports the production of genetic sequences and comes with a kit designed for effective implementation.
Career Highlights
Throughout his career, Sylvain Gariel has made significant strides in his field, which is reflected in his patents and the methodologies he has developed. His work has been instrumental in enhancing the efficiency and accuracy of nucleic acid synthesis, making him a key figure in the biotechnology landscape.
Collaborations
Gariel has collaborated with several noteworthy professionals, including Thomas Ybert and Xavier Godron. These collaborations have fostered innovative projects and have contributed to advancing research in the field of nucleic acids. He has also been associated with renowned companies such as Dna Script and Dna Script Sas, where his expertise has been leveraged to develop cutting-edge technologies in nucleotide synthesis.
Conclusion
Sylvain Gariel continues to be a vital contributor to the innovation landscape in biotechnology. His inventions not only enhance our understanding and capabilities in nucleic acid synthesis but also pave the way for future advancements in genetic research and applications. With a solid foundation of patents and collaborations, Gariel's impact on the field is expected to grow, offering promising developments for both scientific and commercial endeavors.