Company Filing History:
Years Active: 2010-2011
Title: Swarna Gamage: Innovator in Quinoline Derivatives
Introduction
Swarna Gamage is a notable inventor based in Mt. Roskill, New Zealand. She has made significant contributions to the field of medicinal chemistry, particularly in the development of quinoline derivatives for modulating DNA methylation. With a total of two patents to her name, her work has the potential to impact the treatment of various medical conditions.
Latest Patents
Swarna Gamage's latest patents focus on quinoline derivatives that are designed to modulate DNA methylation. These derivatives include compounds such as 4-(4-(4-(quinolin-4-ylamino)benzamido)phenylthio)pyrrolidine-2-carboxylic acid and N-(4-(piperidin-4-ylthio)phenyl)-4-(quinolin-4-ylamino)-benzamide. These compounds are particularly effective in inhibiting the methylation of cytosine at the C-5 position, achieved through selective inhibition of the DNA methyltransferase DNMT1. The patents also detail methods for synthesizing these derivatives and their potential applications in treating conditions like cancer and hematological disorders.
Career Highlights
Swarna Gamage is currently employed at Supergen, Inc., where she continues her research and development efforts. Her innovative work in the field of quinoline derivatives has positioned her as a key figure in medicinal chemistry.
Collaborations
Swarna collaborates with talented individuals such as Pasit Phiasivongsa and Sanjeev Redkar, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Swarna Gamage's contributions to the field of medicinal chemistry through her patents on quinoline derivatives highlight her role as an influential inventor. Her work not only advances scientific knowledge but also holds promise for future medical applications.