Company Filing History:
5 out of 58 
4 out of 149 
1 out of 1,777 
Years Active: 2000-2025
Title: Innovator Spotlight: Svetlana Alexander
Introduction: Svetlana Alexander, an accomplished inventor based in Sunnyvale, CA, has made significant contributions to the field of biomedical research. With a remarkable portfolio of 11 patents, her work mainly focuses on innovative methods of detecting transthyretin and developing antibodies that target tau protein.
Latest Patents: Among her latest inventions, the methods of detecting transthyretin (TTR) stand out. This invention provides techniques for detecting TTR using a capture antibody that preferentially binds to misfolded TTR over its native tetrameric form. Specifically, the capture antibody targets an epitope located within amino acid residues 89-97 or 101-109 of TTR. Noteworthy examples of suitable capture antibodies include 9D5 and 18C5. These methods are instrumental in diagnosing diseases associated with TTR accumulation, such as TTR amyloidosis, and they also play a critical role in monitoring the efficacy of TTR therapeutics. Additionally, her innovation involving antibodies that specifically bind to tau has shown promise in inhibiting or delaying tau-associated pathologies and the symptomatic deterioration linked to these conditions.
Career Highlights: Svetlana has worked with prominent companies such as Prothena Biosciences and Dade Behring Marburg GmbH. Her experience within these organizations has been vital in advancing her research and fostering her innovative spirit.
Collaborations: Throughout her career, Svetlana has collaborated with esteemed colleagues like Robin McDaid Barbour and Philip James Dolan III. These partnerships have allowed her to integrate diverse expertise into her projects, further enhancing the impact of her inventions.
Conclusion: Svetlana Alexander continues to be a pioneering force in her field, dedicating her career to innovations that not only contribute to scientific advancement but also offer hopeful new avenues for diagnosing and treating significant health issues. Her work exemplifies the spirit of innovation that drives progress in biomedical research.