Susan Carol Hagness

Title: Susan Carol Hagness: Innovator in Gene Therapy Delivery Systems

Introduction

Susan Carol Hagness is a prominent inventor based in Madison, Wisconsin. She has made significant contributions to the field of gene therapy, holding a total of 15 patents. Her work focuses on improving the efficiency of gene delivery systems, which has the potential to revolutionize therapeutic approaches in medicine.

Latest Patents

Among her latest innovations is a groundbreaking in vivo gene therapy delivery procedure and device. This 'localizable' systemic gene therapy system substantially increases the transfection efficiency of gene vectors into targeted tissue cells. It also reduces the escape of gene vectors from the targeted tissue volume, which can lead to wasted vectors and undesired immune reactions. The invention features a method to achieve local electroporation and gene vector injection simultaneously in a vascularized organ. It utilizes two double-balloon catheters that create contained volumes in parallel blood vessels, allowing for the introduction of vectors with minimized loss. Additionally, electrodes are included to provide electroporation of the cells at the same location where the vectors are injected.

Career Highlights

Throughout her career, Susan has worked with notable organizations, including the Wisconsin Alumni Research Foundation and Interstitial, LLC. Her expertise in gene therapy has positioned her as a leader in the field, contributing to advancements that enhance therapeutic outcomes.

Collaborations

Susan has collaborated with esteemed colleagues such as Barry Van Veen and Nader Behdad. These partnerships have fostered innovation and have been instrumental in the development of her patented technologies.

Conclusion

Susan Carol Hagness is a trailblazer in the realm of gene therapy, with her inventions paving the way for more effective treatment options. Her dedication to advancing medical technology continues to inspire future innovations in the field.