Sue M Travis

Title: Sue M Travis: Innovator in Antimicrobial Peptides

Introduction

Sue M Travis is a prominent inventor based in Iowa City, IA (US). She has made significant contributions to the field of antimicrobial peptides, holding two patents that showcase her innovative work. Her research focuses on developing peptides that can effectively inhibit microbial growth, which is crucial in combating various infections.

Latest Patents

One of her latest patents is titled "Alpha helical peptides with broad spectrum antimicrobial activity that are insensitive to salt." This invention relates to the use of antimicrobial peptides in inhibiting microbial growth and proliferation. The patent discloses novel antimicrobial truncated peptides based on SMAP 29 and RCAP 18, which contain fewer amino acid residues yet retain bactericidal activity. Additionally, it describes synthetic peptides based on the SMAP 29 protein that also maintain substantial activity despite having fewer amino acid residues and substitutions. The invention further outlines a method for inhibiting microbial growth by administering an effective amount of these peptides or combining them with other antimicrobial agents or antibiotics.

Another significant patent by Travis is "Bactericidal factor in human airway surface fluid and uses thereof." This patent describes a bactericidal factor isolated from the surface fluid of airway epithelial cells. The factor is characterized by a molecular weight of less than 10 kd, heat stability, and broad-spectrum activity against gram-positive and gram-negative bacteria, fungi, and methicillin-resistant Staphylococcus. It also notes that the antimicrobial activity decreases with increasing salt concentration.

Career Highlights

Sue M Travis has worked with esteemed institutions such as the University of Iowa Research Foundation and the University of California. Her work in these organizations has allowed her to advance her research and contribute to the scientific community significantly.

Collaborations

Throughout her career, Travis has collaborated with notable colleagues, including Michael J Welsh and Brian F Tack. These collaborations have likely enriched her research and led to innovative discoveries in the field of antimicrobial peptides.

Conclusion

Sue M Travis is a distinguished inventor whose work in antimicrobial peptides has the potential to make a significant impact on public health. Her patents reflect her dedication to advancing science and improving methods for combating microbial infections.