The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2006
Filed:
Aug. 18, 2000
Brian F. Tack, Iowa City, IA (US);
Paul B. Mccray, Jr., Iowa City, IA (US);
Michael Welsh, Riverside, IA (US);
Sue M. Travis, Iowa City, IA (US);
Robert Lehrer, Santa Monica, CA (US);
Brian F. Tack, Iowa City, IA (US);
Paul B. McCray, Jr., Iowa City, IA (US);
Michael Welsh, Riverside, IA (US);
Sue M. Travis, Iowa City, IA (US);
Robert Lehrer, Santa Monica, CA (US);
The University of Iowa Research Foundation, Iowa City, IA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
The present invention relates to the use of antimicrobial peptides in the inhibition of microbial growth and proliferation. Novel antimicrobial truncated peptides are disclosed which are based upon SMAP 29 and RCAP 18, but which contain a lesser number of amino acid residues yet still retain bactericidal activity. In addition, synthetic peptides based upon the SMAP 29 protein are disclosed which have fewer amino acid residues and include substitutions yet retain substantial activity. The invention also relates to a method of inhibiting microbial growth by administering an effective amount of a peptide in accordance with the invention, or by combining the peptides with other antimicrobial agents or antibiotics.