Sudipto Chakrabortty

Title: Sudipto Chakrabortty: Innovator in Exosomal RNA Research

Introduction

Sudipto Chakrabortty is a prominent inventor based in Waltham, MA (US), known for his significant contributions to the field of exosomal RNA research. With a total of two patents to his name, he has made strides in understanding and utilizing nucleic acids derived from extracellular vesicles.

Latest Patents

Chakrabortty's latest patents include groundbreaking work on the sequencing and analysis of exosome-associated nucleic acids. This invention outlines a series of steps that prepare nucleic acids, both RNA and DNA, isolated from extracellular vesicles for sequencing. This method allows for the efficient detection of a wide diversity of RNAs and DNAs, which can be used to identify various attributes such as gene expression, alternative splicing, and the detection of somatic and germline mutations, including single nucleotide variants and structural variations.

Another notable patent focuses on methods of treating glioblastoma in subjects informed by exosomal RNA signatures. This disclosure relates to treatment methods that utilize gene signatures found in exosomal RNA derived from the subject. The gene signatures include various genes such as FAM229B, ZNF35, and many others. The treatment methods involve measuring the expression levels of these genes in exosomal RNA and administering glioblastoma treatments based on the expression levels.

Career Highlights

Sudipto Chakrabortty is currently associated with Exosome Diagnostics, Inc., where he continues to advance research in the field of exosomal RNA. His work has the potential to significantly impact the diagnosis and treatment of various diseases, particularly glioblastoma.

Collaborations

Chakrabortty collaborates with notable colleagues, including Johan Skog and Dalin Chan, who contribute to the innovative research environment at Exosome Diagnostics, Inc.

Conclusion

Sudipto Chakrabortty's contributions to exosomal RNA research exemplify the intersection of innovation and medical science. His patents not only advance scientific understanding but also hold promise for future therapeutic applications.