This inventor holds 14 USPTO granted patents and 1 published patent application and 2 EPO patents. Top assignees: Life Genetics Lab, LLC, Louisiana State University and Agricultural & Mechanical College, Reliagene Technologies Inc.. Active years: 2006-2022.
Location History:
- Matairie, LA (US) (2018)
- Metairie, LA (US) (2006 - 2021)
- New Orleans, LA (US) (2008 - 2022)
Company Filing History:
7 out of 7 
6 out of 839 
3 out of 3 Years Active: 2006-2022
Title: Sudhir Sinha: Innovator in DNA Analysis and Tumor Measurement
Introduction
Sudhir Sinha is a prominent inventor based in New Orleans, LA, known for his significant contributions to the field of forensic science and oncology. With an impressive portfolio of 14 patents, Sinha has demonstrated his dedication to advancing methodologies that enhance the accuracy and efficiency of DNA analysis.
Latest Patents
Sinha's latest patents showcase innovative approaches to complex scientific challenges. One notable invention is the development of a highly sensitive quantification system for assessing DNA degradation and quality in forensic samples. This process employs a real-time PCR system to quantify two types of retrotransposon interspersed elements within human DNA samples, allowing researchers to determine the extent of DNA degradation. The method's focus on evolutionary unique Alu Yb-lineage subfamily sequences provides a significant advantage in differentiating human from non-human samples. Additionally, his patent outlines the quantification of longer 290 bp sequences of SVA elements and shorter 80 bp sequences of Alu Yb8-lineage through newly designed primers and TaqMan probes, enhancing the precision of forensic analyses.
Another of Sinha's recent patents addresses the measurement of tumor burden in patient-derived xenograft (PDX) mice. This invention encompasses kits and methods for evaluating the tumor load by utilizing blood samples from PDX mice, deploying a real-time PCR system that quantifies both human circulating tumor DNA (ctDNA) and mouse DNA. The simultaneous multiplex PCR amplifications of these sequences, even in small sample volumes, allows for serial evaluations necessary for assessing cancer treatment efficacy in humans.
Career Highlights
Throughout his career, Sudhir Sinha has collaborated with esteemed institutions, notably Life Genetics Lab, LLC, and the Board of Supervisors of Louisiana State University and Agricultural and Mechanical College. His work has had a profound impact on the fields of genetics and cancer research, establishing him as a leader in innovation.
Collaborations
In his journey as an inventor, Sinha has partnered with notable colleagues such as Mark A Batzer and Jerilyn A Walker. These collaborations have further strengthened his research endeavors and contributed to the success of his patents.
Conclusion
Sudhir Sinha’s contributions to the scientific community exemplify the spirit of innovation. His patents, particularly in the areas of DNA degradation analysis and tumor burden measurement, are pioneering advancements that hold the potential for significant advancements in forensic science and oncology. Through his work, he continues to inspire future generations of inventors and researchers.