Subrata Sen

Title: Subrata Sen: Innovator in Osmotic Shock Technology

Introduction

Subrata Sen is a notable inventor based in San Diego, California. He has made significant contributions to the field of biotechnology, particularly in the area of cell processing and recombinant polypeptide production. His innovative approach has led to the development of a unique method for osmotically shocking cells, which has implications for various applications in biotechnology.

Latest Patents

Sen holds a patent for an invention titled "Apparatus and methods for osmotically shocking cells." This patent describes a method of preparing a recombinant polypeptide of interest by fermenting a host cell transformed with a recombinant expression system. The method involves extracting the polypeptide from the periplasm of the host cell by applying continuous osmotic shock. The apparatus includes a first reservoir containing cells in a first solution with higher osmolarity than a second solution, facilitating the osmotic shock process.

Career Highlights

Throughout his career, Subrata Sen has worked with prominent companies such as Dow Agrosciences LLC and Dow Global Technologies LLC. His experience in these organizations has allowed him to refine his skills and contribute to advancements in biotechnology.

Collaborations

Sen has collaborated with notable professionals in his field, including Anant Patkar and Michael L. Chappell. These collaborations have further enriched his work and expanded the impact of his innovations.

Conclusion

Subrata Sen's contributions to biotechnology through his patented methods for osmotically shocking cells highlight his role as an innovator in the field. His work continues to influence the development of recombinant polypeptides and cell processing technologies.