Stuart A Thompson

Title: The Innovative Contributions of Stuart A. Thompson

Introduction

Stuart A. Thompson is a notable inventor based in Whites Creek, TN (US). He has made significant contributions to the field of immunology, particularly in the development of methods for vaccination and detection of antibodies against pathogens. With a total of 6 patents, his work has the potential to impact public health positively.

Latest Patents

One of his latest patents is titled "Method of delivering antigens for vaccination with a live vector." This invention provides a mutant strain in which one or more sapA homologs are altered by an inserted DNA cassette. The encoded S-layer proteins represent a chimera between the native S-layer proteins and a heterologous peptide encoded by the inserted cassette. This heterologous peptide is preferably an immunogen of a pathogen, allowing the mutant strain to immunize a host and develop mucosal and systemic immune responses.

Another significant patent is related to the "iceA gene and related methods." This patent provides a purified IceA protein of Helicobacter pylori, expressed as either an IceA 1 or an IceA 2 variant. It also includes a purified polypeptide fragment of the IceA protein and an antigenic fragment of IceA. Furthermore, it describes a method for detecting the presence of antibodies against H. pylori in a sample, which involves contacting the sample with a purified IceA protein or a specific fragment and detecting the binding of antibodies.

Career Highlights

Stuart A. Thompson is affiliated with Vanderbilt University, where he continues to engage in groundbreaking research. His work has garnered attention for its innovative approaches to vaccine development and pathogen detection.

Collaborations

Throughout his career, Thompson has collaborated with esteemed colleagues, including Martin J. Blaser and Geraldine G. Miller. These collaborations have further enriched his research and contributed to the advancement of immunological studies.

Conclusion

Stuart A. Thompson's contributions to the field of immunology through his patents and research at Vanderbilt University highlight his role as an influential inventor. His innovative methods for vaccination and antibody detection are paving the way for advancements in public health.