Company Filing History:
Years Active: 2015
Title: Innovations of Steven Truscott
Introduction
Steven Truscott is an accomplished inventor based in Royal Oak, MI (US). He has made significant contributions to the field of immunology through his innovative work on MHC class I molecules. His research focuses on the development of novel vaccine strategies that can enhance T cell responses.
Latest Patents
Steven Truscott holds a patent for a disulfide trap MHC class I molecule and its various applications. The patent describes a disulfide trap that comprises an antigen peptide covalently attached to an MHC class I heavy chain molecule by a disulfide bond extending between two cysteines. This innovative design allows for proper oxidation in the endoplasmic reticulum, enabling recognition by T cells. The disulfide trap can be utilized for vaccination purposes, eliciting CD8 T cell responses, and in multivalent MHC/peptide reagents for tracking T cells. Additionally, nucleic acids encoding the disulfide trap can be used as DNA vectors for vaccine development.
Career Highlights
Steven Truscott is affiliated with Washington University, where he continues to advance his research in immunology. His work has garnered attention for its potential applications in vaccine development and T cell enumeration.
Collaborations
He has collaborated with notable colleagues such as Ted H Hansen and Daved Henry Fremont, contributing to the advancement of research in his field.
Conclusion
Steven Truscott's innovative work on disulfide trap MHC class I molecules represents a significant advancement in immunology and vaccine development. His contributions continue to influence the field and hold promise for future therapeutic applications.