Company Filing History:
Years Active: 1994-2000
Title: Innovations in Cellulose Modification: The Contributions of Inventor Steven R. Thomas
Introduction
Steven R. Thomas, a prominent inventor based in Denver, CO, has made significant contributions to the field of genetic engineering, particularly in the area of cellulose modification. With four patents to his name, his work primarily focuses on enhancing the efficiency and stability of enzymes involved in cellulose degradation, which is essential for various industrial applications, including biofuel production.
Latest Patents
Among his latest patents, Thomas has developed innovative methods for the expression and stability of enzymes critical for cellulose modification. One notable patent details the "Expression of enzymes involved in cellulose modification," which encompasses novel compositions and methods aimed at genetically engineering plant cells to express cellulose-degrading enzymes in plastids. This technology has the potential to enhance biomass conversion processes.
Another key patent is focused on the "Method for increasing thermostability in cellulase enzymes." This patent outlines the cloning and expression of the gene encoding Acidothermus cellulolyticus E1 endoglucanase in Pichia pastoris. The resulting modified E1 enzyme, which boasts enhanced thermostability, was produced through two distinct methods: the first involves proteolytic cleavage to remove the cellulose binding domain, while the second employs genetic truncation to express only the catalytic domain of the enzyme.
Career Highlights
Throughout his career, Steven R. Thomas has held positions at renowned organizations, including the Midwest Research Institute and Calgene Corporation. His work in these institutions has allowed him to contribute positively to advancements in biotechnology and genetic engineering.
Collaborations
Collaborating with distinguished scientists has also played a crucial role in Thomas's career. Noteworthy colleagues include Michael E. Himmel and William S. Adney, both of whom have contributed their expertise to projects that focus on cellulose degradation and enzyme functionality.
Conclusion
Overall, Steven R. Thomas's innovations in cellulose modification and enzyme stability represent significant advancements in biotechnology. His patents not only reflect his ingenuity as an inventor but also illustrate the potential impact of his work on various industries that rely on efficient biomass conversion processes. As research continues to evolve, Thomas's contributions will undoubtedly inspire future innovations in the field.