Boston, MA, United States of America

Steven Corsello

USPTO Granted Patents = 3 

 

Average Co-Inventor Count = 4.3

ph-index = 1


Company Filing History:


Years Active: 2025

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3 patents (USPTO):Explore Patents

Title: Innovations in Cancer Treatment by Steven Corsello

Introduction

Steven Corsello is an accomplished inventor based in Boston, MA, known for his significant contributions to cancer research and treatment. With a total of three patents, Corsello has focused on developing innovative methods and compositions for diagnosing and treating various types of cancers. His work has the potential to impact the lives of many patients facing these challenging diseases.

Latest Patents

Corsello's latest patents include groundbreaking research on cancers associated with the loss of chromosome 16Q and low expression of metallothionein proteins. This patent outlines compositions and methods for diagnosing and treating cancers, particularly those that exhibit arm-level loss of chromosome 16q, focal copy loss of 16q13, and/or low expression of metallothionein proteins. The patent highlights the use of three known drugs—disulfiram, elesclomol, and thiram—as therapeutic agents to target cancer cells characterized by these genetic markers.

Another notable patent focuses on aryl hydrocarbon receptor (AHR) activator compounds as cancer therapeutics. This research addresses cancers that exhibit elevated expression of FOXA1 and its gene targets, including specific forms of breast, liver, and prostate cancers. The patent provides insights into the use of adenosine receptor antagonists, such as CGS-15943, MRS-1220, and SCH-58261, as well as their derivatives, to effectively kill cancer cells through AHR activation.

Career Highlights

Corsello has worked with prestigious organizations, including the Broad Institute, Inc. and Dana-Farber Cancer Institute, Inc. His experience in these leading research institutions has allowed him to collaborate with other experts in the field and contribute to significant advancements in cancer treatment.

Collaborations

Some of Corsello's notable coworkers include Ryan Spangler and Rohith Nagari. Their collaborative efforts have further enhanced the research and development of innovative cancer therapies.

Conclusion

Steven Corsello's work in cancer research exemplifies the importance of innovation in the medical field. His patents and collaborations have the potential to lead to new therapeutic options for patients battling cancer. Through his dedication and expertise, Corsello continues to make a meaningful impact in the fight against this disease.

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