The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2026

Filed:

Jul. 27, 2021
Applicants:

Bayer Aktiengesellschaft, Leverkusen, DE;

The Broad Institute, Inc., Cambridge, MA (US);

Dana-farber Cancer Institute, Inc., Boston, MA (US);

Inventors:

Volker Schulze, Hohen Neuendorf, DE;

Anne Mengel, Berlin, DE;

Clara Adelaide Faria Alvares De Lemos, Berlin, DE;

Sven Christian, East Boston, MA (US);

Ulf Bömer, Glienicke, DE;

Roman Hillig, Berlin, DE;

Christian Lechner, Berlin, DE;

Jérémie Xavier Mortier, Berlin, DE;

Stefan Kaulfuss, Berlin, DE;

Steven Corsello, Boston, MA (US);

Katarzyna Handing, Framingham, MA (US);

Amael Madec, Boston, MA (US);

Laura Furst, Somerville, MA (US);

Mrinal Shekhar, Quincy, MA (US);

Markus Berger, Berlin, DE;

Rajesha Rupaimoole, North Billerica, MA (US);

Philip Lienau, Berlin, DE;

Douglas Orsi, Watertown, MA (US);

David Mckinney, Cambridge, MA (US);

Krzysztof Brzezinka, Berlin, DE;

Assignees:

Bayer Aktiengesellschaft, Leverkusen, DE;

The Broad Institute, Inc., Cambridge, MA (US);

Dana-Farber Cancer Institute, Inc., Boston, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61P 35/00 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 487/04 (2006.01); C07F 7/08 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61P 35/00 (2018.01); C07D 401/06 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 487/04 (2013.01); C07F 7/0812 (2013.01);
Abstract

Compounds of formula (I), process for their production and their use as pharmaceuticals.


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