Company Filing History:
2 out of 850 
1 out of 10 Years Active: 2000-2002
Title: Innovator Spotlight: Steven Bossone
Introduction:
Steven Bossone, a highly accomplished inventor based in Lexington, MA, US, has made significant contributions to the field of biotechnology with 3 patents to his name. His groundbreaking inventions in the realm of genetic engineering and protein synthesis have paved the way for advancements in the medical and pharmaceutical industries.
Latest Patents:
1. Genes encoding polypeptides containing signal sequences: Steven Bossone's method of identifying nucleic acid sequences encoding signal peptide-containing proteins involves innovative chimeric constructs containing a KRE9 gene without a signal sequence. This invention is crucial for selecting yeast containing chimeric KRE9 plasmid constructs that encode signal sequences based on their ability to grow on sucrose as the sole carbon source.
2. Secreted proteins and uses thereof: Bossone's invention provides isolated nucleic acid molecules, specifically TANGO 281, which encode proteins downregulated in megakaryocytes lacking the gata-1 transcription factor. Along with antisense nucleic acid molecules and expression vectors, this invention also offers diagnostic, screening, and therapeutic methods utilizing these compositions.
Career Highlights:
During his illustrious career, Steven Bossone has lent his expertise to prominent companies such as Millennium Pharmaceuticals Limited and Millennium Biotherapeutics, Inc. His innovative thinking and scientific prowess have been instrumental in driving research and development efforts in the biopharmaceutical sector.
Collaborations:
Bossone has collaborated with esteemed professionals in the field, including coworkers Sean Anthony McCarthy and Michael Joseph Kuranda. Together, they have worked on cutting-edge projects that have pushed the boundaries of genetic engineering and protein synthesis.
Conclusion:
Steven Bossone's remarkable contributions to the field of biotechnology through his patented inventions underscore his status as a pioneering inventor. His work continues to have a profound impact on the scientific community, shaping the future of genetic research and therapeutic development.