This inventor holds 2 USPTO granted patents. Top assignee: Fraunhofer USA, Inc.. Active years: 2021-2023.
Company Filing History:
Years Active: 2021-2023
Title: Innovations of Stephen Tottey
Introduction
Stephen Tottey is an accomplished inventor based in Swarthmore, PA (US). He has made significant contributions to the field of biotechnology, particularly in the development of fusion proteins and virus-like particles. With a total of 2 patents, Tottey's work has implications for various applications in molecular biology and medicine.
Latest Patents
Tottey's latest patents focus on covalently fused viral coat proteins for the display of target molecules. The first patent describes a fusion protein that includes a target protein, a first recombinant viral coat protein, a second recombinant viral coat protein, and a first linkage peptide. The target protein is positioned at the N-terminus of the first recombinant viral coat protein. The first recombinant viral coat protein is linked to the N-terminus of the first linkage peptide, while the second recombinant viral coat protein is linked to the C-terminus of the first linkage peptide. Both recombinant viral coat proteins are derived from the coat protein of the alfalfa mosaic virus (AIMV). This fusion protein can form a virus-like particle (VLP), allowing the target protein to be displayed on the surface of the VLP. The patent also outlines methods for producing the fusion protein and the VLP, along with their potential uses.
The second patent similarly describes a fusion protein comprising a first recombinant viral coat protein, a second recombinant viral coat protein, and a first linkage peptide. The structure and functionality are akin to the first patent, emphasizing the versatility and potential applications of these fusion proteins in various scientific fields.
Career Highlights
Stephen Tottey is currently employed at Fraunhofer USA, Inc., where he continues to innovate and contribute to advancements in biotechnology. His work is characterized by a strong focus on the practical applications of his inventions, aiming to bridge the gap between research and real-world solutions.
Collaborations
Tottey collaborates with Konstantin Musiychuk, a fellow researcher, to further explore the potential of their innovations in the field of biotechnology.
Conclusion
Stephen Tottey's contributions to the field of biotechnology through his innovative patents and collaborations highlight his role as a significant inventor. His work on fusion proteins and virus-like particles has the potential to impact various applications in molecular biology and medicine.