Company Filing History:
Years Active: 2021-2025
Title: The Innovative Mind of Stephen Jordan Fleming
Introduction: Stephen Jordan Fleming is a prominent inventor based in Cincinnati, Ohio, recognized for his groundbreaking contributions to the field of polymer translocation through nanopores. With a total of two patents to his name, he continues to push the boundaries of science and technology, making significant strides in the understanding and functionality of polymer molecules.
Latest Patents: One of Stephen Fleming's latest patents is titled "Deterministic Stepping of Polymers Through a Nanopore." This innovative system includes first and second fluidic reservoirs in fluidic communication with a nanopore, forming a comprehensive fluidic path. The system features an enzyme clamp that is reversibly bound to a sequential plurality of polymer subunits of a target polymer molecule in an ionic solution. Notably, the clamp has an outer diameter greater than that of the nanopore itself. The invention utilizes an electrical circuit with electrodes to apply a voltage bias across the nanopore, and a pulse generator is used to apply control pulses, which enable the step-wise movement of the clamp along the polymer subunits. Remarkably, the system operates without any fuel source for the clamp, showcasing an efficient method for controlling polymer translocation.
Career Highlights: Stephen Fleming's career has been marked by innovations that bridge the gap between science and practical applications. His research and inventions demonstrate a deep understanding of the interactions between polymers and nanopores, providing valuable insights into molecular dynamics and translocation processes.
Collaborations: Throughout his career, Fleming has collaborated with esteemed colleagues, including Daniel Branton and Jene A. Golovchenko. These collaborations have enriched his research efforts and contributed to the advancement of the technologies pertaining to nanopores and polymers.
Conclusion: Stephen Jordan Fleming stands out as an influential inventor in the realm of polymer technology. His latest patent highlights the potential of deterministic stepping of polymers through nanopores, reflecting both ingenuity and a commitment to advancing scientific knowledge. As he continues his work at Harvard College, his contributions will undoubtedly pave the way for future innovations and discoveries in this exciting field.