Stephen J Gunstream

Title: Innovations by Stephen J Gunstream

Introduction

Stephen J Gunstream is a notable inventor based in San Francisco, CA. He holds a total of 9 patents that showcase his contributions to the field of microfluidics and calibration systems. His work has significantly advanced the capabilities of various technologies used in scientific research and diagnostics.

Latest Patents

One of his latest patents is focused on microfluidic devices and methods for their use. Exemplary embodiments provide microfluidic devices that include an array of M×N reaction sites formed by intersecting a first and second plurality of fluid channels of a flow layer. The flow layer can have a matrix design and/or a blind channel design to analyze a large number of samples under a limited number of conditions. Additionally, the microfluidic device can include a control layer with a valve system for regulating solution flow through fluid channels. By aligning the control layer with the fluid channels, the detection of the microfluidic devices can be improved by piping lights to and from the reaction sites. Furthermore, guard channels can be included for thermal cycling and/or reducing evaporation from the reaction sites.

Another significant patent is for a system and method for interpolative calibration. This innovation provides systems and methods for calibrating emission data or other information signals collected during a polymerase chain reaction (PCR) or other reactions. Calibration of multiple detectable materials can be achieved during a single cycle or run, or during multiple runs of the reaction. Interpolation can be used to determine values for emission data or other information signals that were not taken, leading to a more accurate reading of emission data.

Career Highlights

Stephen has worked with prominent companies in the biotechnology sector, including Applied Biosystems, LLC and Life Technologies Corporation. His experience in these organizations has allowed him to develop and refine his innovative ideas, contributing to advancements in the field.

Collaborations

Throughout his career, Stephen has collaborated with notable professionals such as Mark F Oldham and Michael R Gambini. These collaborations have further enriched his work and expanded the impact of his inventions.

Conclusion

Stephen J Gunstream is a distinguished inventor whose work in microfluidics and calibration systems has made a significant impact on scientific research and diagnostics. His innovative patents and collaborations highlight his contributions to advancing technology in these fields.