Stephen H Herrmann

Title: The Innovative Contributions of Stephen H Herrmann

Introduction

Stephen H Herrmann is a notable inventor based in Stowe, MA (US), recognized for his significant contributions to the field of protein production. With a total of 6 patents to his name, Herrmann has made strides in developing systems and methods that enhance the yield of proteins of interest through genetic engineering.

Latest Patents

One of Herrmann's latest patents focuses on systems and methods for protein production. This invention employs genetically-engineered animal or plant cells that possess modified protein folding or processing capacities. The invention features genetically-engineered cells that include one or more recombinant expression cassettes, which encode a protein of interest and a polypeptide functional in the unfolded protein response (UPR) pathway of the cells. The co-expression of this polypeptide significantly increases the yield of the protein of interest in the genetically-engineered cells. In one example, the genetically-engineered cells are animal cells, and the co-expressed polypeptide acts as a component or modulator of an XBP1- or ATF6-mediated UPR pathway.

Career Highlights

Throughout his career, Stephen H Herrmann has worked with prominent organizations such as Genetics Institute, Inc. and Wyeth. His experience in these companies has contributed to his expertise in the field of biotechnology and protein production.

Collaborations

Herrmann has collaborated with notable colleagues, including Stephen L Swanberg and Zhijian Lu, further enhancing his innovative work in protein production.

Conclusion

Stephen H Herrmann's contributions to the field of protein production through his innovative patents and collaborations highlight his role as a significant inventor. His work continues to influence advancements in biotechnology and genetic engineering.