Mountain View, CA, United States of America

Stefanie Yukiko Nishimura

USPTO Granted Patents = 6 

Average Co-Inventor Count = 14.0

ph-index = 3

Forward Citations = 105(Granted Patents)


Company Filing History:


Years Active: 2014-2024

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6 patents (USPTO):

Title: Stefanie Yukiko Nishimura: Innovator in Nucleotide Transient Binding Methods

Introduction

Stefanie Yukiko Nishimura is a prominent inventor based in Mountain View, CA (US). She has made significant contributions to the field of biotechnology, particularly in the development of methods for sequencing nucleic acids. With a total of 6 patents to her name, her work has advanced the understanding and application of polymerase-dependent techniques.

Latest Patents

One of her latest patents focuses on nucleotide transient binding for sequencing methods. This invention provides compositions and systems that utilize polymerase-dependent, nucleotide transient-binding methods. The methods are designed to deduce the sequence of a template nucleic acid molecule and conduct single nucleotide polymorphism (SNP) analyses. The innovation relies on the observation that the polymerase transient-binding time for a complementary nucleotide is longer than that for a non-complementary nucleotide. The labeled nucleotides bind transiently to the polymerase in a template-dependent manner without incorporation. These methods can be performed under various reaction conditions that allow for the transient binding of complementary or non-complementary nucleotides to a polymerase while inhibiting nucleotide incorporation.

Career Highlights

Stefanie is currently associated with Life Technologies Corporation, where she continues to push the boundaries of genetic research and sequencing technologies. Her work has been instrumental in enhancing the efficiency and accuracy of nucleic acid sequencing.

Collaborations

Throughout her career, Stefanie has collaborated with notable colleagues, including Peter B Vander Horn and Cheng-Yao Chen. These partnerships have fostered innovation and contributed to the success of her projects.

Conclusion

Stefanie Yukiko Nishimura's contributions to nucleotide transient binding methods exemplify her dedication to advancing biotechnology. Her innovative patents and collaborations highlight her role as a leading inventor in the field.

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