Stefan Hepbildikler

Title: The Innovative Contributions of Stefan Hepbildikler

Introduction

Stefan Hepbildikler is a notable inventor based in Munich, Germany. He has made significant contributions to the field of biochemistry, particularly in the area of polypeptide purification. With a total of 7 patents to his name, his work has advanced the methodologies used in the separation and purification of polypeptides.

Latest Patents

One of his latest patents is a method for the separation of monomeric polypeptides from aggregated polypeptides. This innovative method involves providing a solution that contains both monomeric and aggregated forms of the polypeptide, followed by a series of chromatographic techniques to isolate the desired monomeric form. Another significant patent focuses on immunoglobulin aggregate removal, utilizing underivatized controlled pore glass (uCPG) to selectively bind high molecular weight compounds from recombinantly produced polypeptides. This method has shown impressive results, achieving a removal rate of 80% to 95% of high molecular weight compounds while maintaining a yield of 80% to 90% of the polypeptide.

Career Highlights

Stefan Hepbildikler is currently employed at Hoffmann-La Roche Inc., where he continues to innovate and contribute to the field of biochemistry. His work has not only advanced scientific understanding but has also had practical applications in the pharmaceutical industry.

Collaborations

Throughout his career, Stefan has collaborated with esteemed colleagues such as Wolfgang Kuhne and Eva Rosenberg. These collaborations have further enriched his research and have led to the development of groundbreaking methodologies in polypeptide purification.

Conclusion

Stefan Hepbildikler's contributions to the field of biochemistry are noteworthy and impactful. His innovative patents and collaborative efforts continue to shape the future of polypeptide purification techniques.