Location History:
- Prinzerdorf, AT (2014)
- Prinzersdorf, AT (2014 - 2023)
Company Filing History:
Years Active: 2014-2023
Title: Innovations of Stefan Haider
Introduction
Stefan Haider is a notable inventor based in Prinzersdorf, Austria. He has made significant contributions to the field of polymer chemistry, particularly in the development of conjugation methods for therapeutic proteins. With a total of 12 patents to his name, Haider's work has the potential to impact various medical applications.
Latest Patents
One of Haider's latest patents is focused on nucleophilic catalysts for oxime linkage. This invention relates to materials and methods for conjugating a water-soluble polymer to an oxidized carbohydrate moiety of a therapeutic protein. The process involves contacting the oxidized carbohydrate moiety with an activated water-soluble polymer under conditions that facilitate conjugation. Specifically, the water-soluble polymer contains an active aminooxy group, allowing for the formation of an oxime or hydrazone linkage. The conjugation is carried out in the presence of a nucleophilic catalyst, enhancing the efficiency of the process.
Another significant patent by Haider involves blood coagulation protein conjugates. This invention also focuses on the conjugation of a water-soluble polymer to an oxidized carbohydrate moiety, specifically within blood coagulation proteins. Similar to his previous patent, this method utilizes an active aminooxy group to form an oxime linkage. In one embodiment, the conjugation is performed in the presence of the nucleophilic catalyst aniline, and the generated oxime linkage can be stabilized by reduction with NaCNBH to form an alkoxyamine linkage.
Career Highlights
Throughout his career, Stefan Haider has worked with prominent companies such as Baxalta GmbH and Baxter International Inc. His experience in these organizations has allowed him to refine his expertise in polymer chemistry and therapeutic applications.
Collaborations
Haider has collaborated with notable colleagues, including Juergen Siekmann and Hanspeter Rottensteiner. These collaborations have contributed to the advancement of his research and innovations in the field.
Conclusion
Stefan Haider's contributions to polymer chemistry and therapeutic protein conjugation are noteworthy. His innovative patents and collaborations reflect his commitment to advancing medical science through his inventions.
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