Company Filing History:
Years Active: 2006-2022
Title: Innovations of Stefan H I Kappe
Introduction
Stefan H I Kappe is a prominent inventor based in Seattle, WA, known for his significant contributions to the field of malaria research. He holds a total of 8 patents, showcasing his dedication to advancing medical science and improving public health.
Latest Patents
One of his latest patents is focused on "Doubly attenuated late liver stage malaria parasites and related compositions and methods." This invention involves genetically manipulating malaria parasites to interrupt the functionality of specific genes, LISP2 and PlasMei2. The resulting doubly attenuated malaria parasites are designed to stimulate vertebrate host immune systems effectively. By halting lifecycle progression in the late liver stage, these parasites provide a comprehensive antigenic presentation that represents wildtype liver stage parasites. Additionally, the invention includes blood stage and gametocyte antigens to enhance immune stimulation and prevent disease transmission related to blood stage parasites.
Career Highlights
Stefan H I Kappe has worked with notable organizations, including the Seattle Biomedical Research Institute and Ruprecht-Karls-Universität Heidelberg. His work in these institutions has significantly contributed to the understanding and treatment of malaria.
Collaborations
Throughout his career, Kappe has collaborated with esteemed colleagues such as Kai-Uwe C Matuschewski and Ann-Kristin Mueller. These partnerships have furthered research efforts and innovations in malaria treatment.
Conclusion
Stefan H I Kappe's work exemplifies the impact of innovative research in combating malaria. His patents and collaborations highlight his commitment to improving health outcomes through scientific advancements.