The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 25, 2010
Filed:
Jun. 22, 2005
Stefan H. I. Kappe, Seattle, WA (US);
Kai-uwe C. Matuschewski, Berlin, DE;
Ann-kristin Mueller, Dossenheim, DE;
Stefan H. I. Kappe, Seattle, WA (US);
Kai-Uwe C. Matuschewski, Berlin, DE;
Ann-Kristin Mueller, Dossenheim, DE;
Seattle Biomedical Research Institute, Seattle, WA (US);
Abstract
The invention provides methods for inducing an immune response in a vertebrate host against a protozoan parasite, comprising administering to the host a live protozoan parasite that is genetically engineered to disrupt a stage-specific gene function that is required by the protozoan parasite to establish a secondary infection in the vertebrate host. Representative protozoan parasites belong to the phyla Apicomplexa and Kinetoplastida. The vertebrate host may be a mammal or a bird.