Company Filing History:
Years Active: 1999-2006
Title: The Innovative Contributions of Stefan Gruenwald
Introduction
Stefan Gruenwald is a notable inventor based in Encinitas, California. He has made significant contributions to the field of flow cytometry and cellular biology. With a total of 3 patents, his work focuses on the detection of protein conformations in single cells.
Latest Patents
Gruenwald's latest patents include methods, reagents, and kits that allow for the flow cytometric determination of the phosphorylation status of the retinoblastoma susceptibility gene protein (pRB) in individual cells. These methods enable the measurement of the hypophosphorylated, active form of pRB, either as an absolute quantity or as a proportion of total cellular pRB. Additionally, his patents describe methods that correlate pRB phosphorylation status with cell cycle phases and protein components of the cell cycle. His work also demonstrates the screening of chemical compounds for antiproliferative and antineoplastic activity using flow cytometric assays.
Career Highlights
Throughout his career, Gruenwald has worked with prominent companies such as Becton Dickinson and Company Limited and Pharmingen. His expertise in flow cytometry has positioned him as a key figure in the development of innovative methodologies in cellular analysis.
Collaborations
Gruenwald has collaborated with esteemed colleagues, including Zbigniew Darzynkiewicz and Frank Traganos. These collaborations have further enhanced the impact of his research and innovations in the field.
Conclusion
Stefan Gruenwald's contributions to the field of flow cytometry and cellular biology are noteworthy. His innovative patents and collaborations have significantly advanced the understanding of protein conformations in single cells.