Stacey A L Tom-Yew

Title: Stacey A L Tom-Yew: Pioneering Advances in Antigen Binding Polypeptides

Introduction

Stacey A L Tom-Yew is an innovative inventor based in Coquitlam, Canada. With a remarkable portfolio of 7 patents, he has made significant contributions to the field of immunology and biotechnology through his groundbreaking inventions.

Latest Patents

Among his latest patents, Tom-Yew has developed two notable inventions related to modified antigen binding polypeptide constructs and engineered immunoglobulin heavy chain-light chain pairs. His first patent presents heterodimer pairs that consist of an immunoglobulin heavy chain or its fragment accompanied by an immunoglobulin light chain or its fragment. This invention emphasizes the importance of amino acid modifications in the CH1, CL, VH, and VL domains. These modifications facilitate preferential pairing between the heavy and light chains, ensuring that specific combinations are co-expressed effectively in cells.

The second patent elaborates on similar heterodimer pair constructs, enhancing the concept of engineered immunoglobulin variations. Tom-Yew's work ensures that each heavy chain preferentially pairs with its designated light chain, optimizing the functionality of the pairs in biological applications.

Career Highlights

Stacey A L Tom-Yew's career is marked by his role at Zymeworks Inc., where he collaborates with fellow experts in the field. His patents reflect a deep understanding of immunological processes and showcase his drive to innovate within the scientific community.

Collaborations

In his current position, Tom-Yew works alongside talented individuals such as Dunja Urosev and Surjit Bhimarao Dixit. Their collaborative efforts enhance the research capabilities at Zymeworks Inc. and contribute to the pioneering advancements in antibody engineering.

Conclusion

Stacey A L Tom-Yew's contributions to the field of immunology through his innovative patents illustrate his dedication to advancing biotechnology. His work not only impacts scientific research but also holds potential for significant therapeutic applications, solidifying his reputation as a respected inventor in the industry.