The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 2016
Filed:
Mar. 28, 2011
Igor D'angelo, Port Moody, CA;
Dustin Bleile, Vancouver, CA;
Stacey A. L. Tom-yew, New Westminster, CA;
Eric Escobar-cabrera, Burnaby, CA;
Paula I. Lario, Vancouver, CA;
Anders Ohrn, Vancouver, CA;
David K. Y. Poon, Richmond, CA;
Surjit B. Dixit, Richmond, CA;
Igor D'Angelo, Port Moody, CA;
Dustin Bleile, Vancouver, CA;
Stacey A. L. Tom-Yew, New Westminster, CA;
Eric Escobar-Cabrera, Burnaby, CA;
Paula I. Lario, Vancouver, CA;
Anders Ohrn, Vancouver, CA;
David K. Y. Poon, Richmond, CA;
Surjit B. Dixit, Richmond, CA;
Zymeworks Inc., Vancouver, British Columbia, CA;
Abstract
Rationally designed antibodies and polypeptides that comprise multiple Fc region amino acid substitutions that synergistically provide enhanced selectivity and binding affinity to a target Fc receptor are provided. The polypeptides are mutated at multiple positions to make them more effective when incorporated in antibody therapeutics than those having wild-type Fc components.