Company Filing History:
2 out of 321 
2 out of 4 Years Active: 2014-2015
Title: The Innovative Contributions of Inventor Srok Ho Yoo
Introduction
Srok Ho Yoo is a prominent inventor based in Daejeon, South Korea, recognized for his significant contributions to the field of biomedical inventions. With a total of two patents to his name, he has made notable advancements in the prevention and treatment of autoimmune diseases.
Latest Patents
Srok Ho Yoo's most recent patents include groundbreaking inventions that focus on the dual antagonism of TNF-alpha and IL-21, as well as TNF-alpha and TWEAK.
The first patent involves the development of a TNFR2-IL21R fusion protein that acts as a double-antagonist targeting TNF-alpha and IL-21. This composition effectively reduces the secretion of inflammatory cytokines while increasing the production of anti-inflammatory cytokines. Notably, it also suppresses the differentiation of osteoclasts more efficiently than existing single protein treatments. This innovative approach has shown excellent treatment effects on arthritis in a CIA (Collagen-Induced Arthritis) mouse model and holds promise for the prevention and treatment of autoimmune rheumatoid arthritis by enhancing the expression of Treg cells.
The second patent, focusing on the TNFR2-TWEAKR fusion protein, acts as a dual antagonist to TNF-alpha and TWEAK, both recognized as major contributors to autoimmune arthritis. This composition has demonstrated superior efficacy over single protein treatments by significantly reducing IL-17 secretion in Th17 cells while promoting IL-10 production in Treg cells. The effective treatment results further establish this invention as a noteworthy solution in combating autoimmune diseases.
Career Highlights
Srok Ho Yoo has worked with renowned institutions such as the Korea Research Institute of Bioscience and Biotechnology and the Industry-Academic Cooperation Foundation at the Catholic University of Korea. His work in these organizations reflects his dedication to advancing research and innovation in the field of biosciences.
Collaborations
Throughout his career, Srok Ho Yoo has collaborated with several prominent researchers, including Young Woo Park and Ki Won Jo. These partnerships have further enhanced his research efforts and accelerated the development of new therapeutic options for autoimmune diseases.
Conclusion
Srok Ho Yoo's contributions to the field of medicine through his patents highlight his role as an innovator in treating autoimmune diseases. His developments in dual antagonists present promising avenues for future research and therapeutic applications, paving the way for improved health outcomes in patients suffering from autoimmune conditions.