Company Filing History:
Years Active: 2015-2023
Title: Srikumar Sengupta: Innovator in Hepatic Research
Introduction
Srikumar Sengupta is a prominent inventor based in Madison, WI (US). He has made significant contributions to the field of hepatic research, holding a total of four patents. His work focuses on the culture and maintenance of human liver cells, which has important implications for medical research and therapies.
Latest Patents
Sengupta's latest patents include innovative methods for the expansion and maintenance of adult primary human hepatocytes in culture. He has developed techniques for the derivation, culture, and maturation of small hepatic progenitor cells. Additionally, he has created methods for generating uniform hepatocytes from human embryonic stem cells by inhibiting TGF-beta. These methods are crucial for maintaining the expression of hepatic genes in human hepatocytes and ensuring the functional hepatic enzyme activity of primary hepatocytes in culture. His disclosures also encompass new methods for deriving a population of pure hepatocytes without the need for selecting or sorting the cells from cultured pluripotent cells.
Career Highlights
Srikumar Sengupta is associated with the Wisconsin Alumni Research Foundation, where he continues to advance his research in hepatic cell culture. His work has garnered attention for its potential to improve liver disease treatments and regenerative medicine.
Collaborations
Sengupta collaborates with notable researchers in his field, including James A. Thomson, who is recognized for his contributions to stem cell research. Their partnership enhances the impact of their research on hepatic cell applications.
Conclusion
Srikumar Sengupta's innovative work in hepatic research and his contributions to the field through his patents highlight his role as a leading inventor. His advancements in cell culture techniques are paving the way for future developments in liver therapies.