Company Filing History:
Years Active: 2005-2017
Title: Spencer Dreher: Innovator in Pharmaceutical Chemistry
Introduction
Spencer Dreher, an accomplished inventor based in Metuchen, New Jersey, has made significant contributions in the field of pharmaceutical chemistry. With three patents to his name, Dreher's work focuses on innovative solutions for medical treatment, particularly in the areas of disease therapy and prevention.
Latest Patents
One of Dreher's notable inventions is related to soluble guanylate cyclase activators. This invention encompasses a compound of Formula I or a pharmaceutically acceptable salt thereof, which effectively modulates the body's production of cyclic guanosine monophosphate (cGMP). The compounds are designed to be suitable for the therapy and prophylaxis of diseases associated with a disturbed cGMP balance. Furthermore, the invention outlines processes for preparing these compounds, as well as pharmaceutical preparations that incorporate them.
Another significant patent involves a process for making N-sulfonated-amino acid derivatives, which are critical for creating potent lethal factor (LF) inhibitors for treating anthrax. This invention introduces a novel and effective method that uses a high-yielding and highly enantioselective asymmetric hydrogenation reaction of tetrasubstituted ene-sulfonamide acids or esters, ultimately leading to the synthesis of these important LF inhibitors.
Career Highlights
Throughout his career, Spencer Dreher has worked with reputable organizations, including Merck & Company and Merck Sharp & Dohme Corporation. His tenure in these esteemed institutions has allowed him to channel his research skills into practical pharmaceutical innovations.
Collaborations
Dreher has collaborated with talented individuals in the industry, notably Norihiro Ikemoto and Xiaoqing Han. These partnerships have facilitated the exchange of ideas and paved the way for significant advancements in drug development.
Conclusion
Spencer Dreher's contributions to the field of pharmaceutical chemistry not only enhance our understanding of disease treatment but also underline the importance of collaboration in scientific advancements. With a strong foundation in innovation, Dreher continues to pave the way for future developments in medicine.