Sou-Chan Chang

Title: Innovations by Sou-Chan Chang in Pharmaceutical Manufacturing

Introduction

Sou-Chan Chang is a notable inventor based in Westbury, NY, who has made significant contributions to the field of pharmaceutical manufacturing. He holds two patents that focus on innovative processes for producing paroxetine solid dispersions, which are crucial for enhancing the solubility and bioavailability of poorly soluble drugs.

Latest Patents

Chang's latest patents include an "Aqueous process for manufacturing paroxetine solid dispersions" and a "Process for manufacturing paroxetine solid dispersions." The aqueous process involves mixing paroxetine free base or a pharmaceutically acceptable paroxetine salt with water and a polymer, followed by drying to create a composition that is free from crystalline form. This method eliminates the need for organic solvents, making it more environmentally friendly and suitable for pharmaceutical applications. The second patent details a process that utilizes a solvent or fusion method to create solid dispersions of poorly soluble drugs, specifically focusing on paroxetine free base. This approach allows for lower temperatures during the fusion process and reduces the volume of organic solvents required.

Career Highlights

Sou-Chan Chang is currently employed at Endo Pharmaceuticals Inc., where he continues to innovate in the pharmaceutical sector. His work has significantly impacted the development of formulations that improve drug delivery and patient outcomes.

Collaborations

Chang collaborates with esteemed colleagues such as William A Hein, II and Philip J Krape, contributing to a dynamic research environment that fosters innovation in drug manufacturing.

Conclusion

Sou-Chan Chang's contributions to pharmaceutical manufacturing through his innovative patents demonstrate his commitment to improving drug formulations and patient care. His work continues to influence the industry positively.