The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2001
Filed:
May. 07, 1998
Applicant:
Inventors:
William A. Hein, II, Hasbrouck Heights, NJ (US);
Sou-Chan Chang, Westbury, NY (US);
Huai-Hung D. Kao, Syosset, NY (US);
Assignee:
Endo Pharmaceuticals, Inc., Chadds Ford, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 ; A61K 9/20 ;
U.S. Cl.
CPC ...
A61K 9/14 ; A61K 9/20 ;
Abstract
A process for preparing solid, amorphous paroxetine comprising: (A) mixing paroxetine free base or a pharmaceutically acceptable paroxetine salt with water and pharmaceutically acceptable polymer; and (B) drying to form a composition comprising amorphous paroxetine and polymer, eliminating the need for organic solvents common for the solvent process. The resultant amorphous solid paroxetine composition is free from crystalline form, and yet has good handling properties, making it suitable for pharmaceutical use in the traditional tablet dosage form.