Baltimore, MD, United States of America

Soloman H Snyder


Average Co-Inventor Count = 7.0

ph-index = 1

Forward Citations = 1(Granted Patents)


Company Filing History:


Years Active: 2006

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1 patent (USPTO):Explore Patents

Title: Soloman H Snyder: Innovator in Neurobiology

Introduction

Soloman H Snyder is a prominent inventor and researcher based in Baltimore, MD. He is known for his significant contributions to the field of neurobiology, particularly in understanding the role of D-serine in the brain. His work has implications for treating various neurological conditions.

Latest Patents

One of Snyder's notable patents is related to the enzyme mammalian serine racemase. This enzyme catalyzes the conversion of L-serine to D-serine, which is crucial for the functioning of NMDA receptors in the brain. The patent highlights that high levels of D-serine are found in the mammalian brain, where it acts as an endogenous ligand for these receptors. The purified serine racemase has a molecular weight of 37 kDa and requires pyridoxal 5'-phosphate for its activity. It is highly selective for L-serine and does not racemize other amino acids. Additionally, the patent discusses the identification of polynucleotide sequences that encode mammalian serine racemase, including that of humans. Compounds that modulate the activity of this enzyme are proposed to be useful in treating conditions involving NMDA receptor overstimulation, such as stroke and various neurodegenerative diseases.

Career Highlights

Soloman H Snyder is affiliated with The Johns Hopkins University, where he has made significant strides in neurobiological research. His work has not only advanced scientific understanding but has also paved the way for potential therapeutic applications.

Collaborations

Snyder has collaborated with notable colleagues, including Herman Wolosker and Kevin Sheth, to further explore the implications of his research in neurobiology.

Conclusion

Soloman H Snyder's innovative work in the field of neurobiology, particularly through his patent on mammalian serine racemase, showcases his commitment to advancing medical science. His contributions have the potential to impact the treatment of various neurological disorders significantly.

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