Location History:
- Parma, IT (2009 - 2020)
- Heidelberg, DE (2023)
Company Filing History:
3 out of 155 
1 out of 1 
1 out of 329 
Years Active: 2009-2023
Title: Simone Ottonello: Innovator in Immunology
Introduction
Simone Ottonello is a prominent inventor based in Parma, Italy. She has made significant contributions to the field of immunology, particularly in the development of vaccines and antibody constructs. With a total of 5 patents, her work has the potential to impact medical science and therapeutic practices.
Latest Patents
One of her latest patents is focused on a cutaneous papilloma virus vaccine. This invention relates to an immunogenic polypeptide that comprises a multitude of papillomavirus (PV) L2 N-terminal peptides corresponding to amino acids 20 to 50 of the L2 polypeptide of HPV16. The HPV L2 N-terminal peptides are derived from at least four different cutaneous HPV genotypes. This immunogenic polypeptide is intended for use in medicine and vaccination against cutaneous HPV infection and/or mucosal HPV infection. Additionally, the invention includes a polynucleotide encoding the immunogenic polypeptide and various methods for producing related antibodies.
Another significant patent involves VHH constructs for diverting an immune response. This invention presents a novel VHH construct that can be bound by a complete antibody without impairing the antigen-binding properties of the VHH construct. It also includes an antibody construct comprising this VHH construct and a kit for use in immunodiagnostics or therapeutics. This innovation allows for the redirection of a patient's existing immunity toward a different antigen.
Career Highlights
Throughout her career, Simone has worked with notable organizations such as the Deutsches Krebsforschungszentrum and Preclinics Gesellschaft für Präklinische Forschung mbH. Her experience in these institutions has contributed to her expertise in immunology and vaccine development.
Collaborations
Simone has collaborated with esteemed colleagues, including Angelo Bolchi and Martin Müller. These partnerships have further enriched her research and innovations in the field.
Conclusion
Simone Ottonello is a trailblazer in immunology, with her patents paving the way for advancements in vaccine development and therapeutic applications. Her contributions are poised to make a lasting impact on public health and medical science.